Dr. Sakezo Sado and Mi-Kun from "Space Battleship Yamato". In the series' English dub (titled "Star Blazers"), they are known as "Dr. Sakezo Sane" and "Mimi".

To all fans of Leiji Matsumoto anime (including "Star Blazers", "Captain Harlock", "Galaxy Express 999", "Interstellar 5555") here, please vote and favorite it, and try help those anime gain more popularity here on the site, partly by submitting your own fan art/wallpapers/e-cards/cosplay photos/fan manga that are Leiji matsumoto-themed to this site, regardless of their relaese dates (ex: sometime in the 1970s). Those are anime worth remembering, because they helped shpae the Anime industry's history, including for Anime's Space Adventure genre. Thanks!