One word: Hemorrhoids.
If you don't understand, well, picture yourself out in public just minding your own business when suddenly it feels like something has stabbed you right in the butt, or better yet, imagine tiny claws scratching at the inside of your...Ahem, backside.
Oh, and they're very itchy too, but of course you can't really relieve that in public, unless you want to embarrass yourself and get stares from strangers.
That's basically what I have to deal with everyday.