Ichigo Momomiya (桃宮 いちご, Momomiya Ichigo) is the series' main protagonist and the leader of the Mew Mews. Ichigo is merged with the DNA of the Iriomote Cat, giving her the ability to transform into Mew Ichigo, a powerful and heroic cat girl. The transformation also causes her to exhibit various feline mannerisms while in her human form. At first, her cat ears and tail appear when she is excited, but eventually her cat DNA grows strong enough that turn when she is very excited she turns into a small black cat. She remains in a cat form until someone – human or animal – kisses her.

At the start of the series, Ichigo has a crush on Masaya Aoyama. Although she believes that he is oblivious to her feelings, he later returns them and they begin dating. Midway through the series, Ichigo gains a mysterious protector, the Blue Knight. Throughout the series, Ichigo repeatedly rejects repeated advances by Kish and although she can not accept his final declaration of love, she cries over his death and holds him as he dies.Ichigo dies after transferring her own life force into Masaya after Masaya kills himself and Deep Blue. She is subsequently revived by the last of the mew aqua which was housed within Masaya. Before Masaya goes off to study abroad in England at the end of the series, Ichigo participates in a mock wedding with Masaya. Tokyo Mew Mew a La Mode reveals that Ichigo lost all of her Mew Mew powers and joined Masaya in England, but returned to Japan when her powers began to manifest again to aid in the battle against the Saint Rose Crusaders.