I've gone on record for saying that the core cast of Soul Eater consists of rejects from other anime and my opinion is still very much the same but can this work?

Maka Albarn is basically by the books a straight A student, she's not a bad character per say but she never really left an impact.
Soul Eater Evans dresses like a 90s shonen protagonist, trying to keep a cool persona, but every so often he can pull it off without feeling forced.
Black Star is early Naruto taken to it's logical extreme and pulls it off with flying colours.
Tsubaki surprisingly works as an audience surrogate, she's often the one who keeps everyone in check especially Black Star
Death the Kid is argubly my favourite character, the way the anime handles a character destined to be overpowered is a stroke of genius and gives him a personality worthy of his design.
Liz feels like Death the Kid's babysitter while Patty is the free spirited child channelling the energy of Ed from Cowboy Bebop, both characters don't really standout as their design is generic, but I generally remember Patty more than Liz.

Maka Albarn - 6.7/10
Soul Eater Evans - 8.1/10
Blackstar - 8.5/10
Tsubaki Nakatsukasa - 7.5/10
Death the Kid - 9.2/10
Liz Thompson - 6.3/10
Patty Thompson - 7.3/10