Throughout my childhood I grew up on Nicktoons much in the same way I grew up on Disney & Cartoon Network, but there were a few gems that I missed mainly because I lost a lot of interest in cartoon channels when they started running out of ideas or thinking that kid sitcoms are worth more money.
One of the gems I missed was Danny Phantom.

Danny Phantom is by Butch Hartman of Fairly Odd Parents fame, which seems to play against type being a superhero cartoon but Hartman seems to manage just fine.
The story is about Danny Fenton, (I see what you did there) an unpopular teenager who attends Casper High School in the town of Amity Park. (Barely into the review and already there are two reference jokes)
Danny's parents are working on a ghost portal to try and bridge the gap between spirit and human worlds when it doesn't work until Danny's friend Sam persuades him to switch on the machine only for Danny's DNA to get fused with Ectoplasm, making him half ghost. After fighting a malevolent ghost, Danny decides to become a superhero in order to stop other evil ghosts, alongside friends Sam and Tucker.
This setup is familiar to anyone who's been watching Kim Possible & American Dragon, as the cartoon is pretty much those shows, only done by Nickelodeon instead of Disney; its another example of Nickelodeon jumping on a current trend but unlike Nicktoons sad ripoff of Regular Show, Sanjay & Craig, Danny Phantom not only works but manages to surpass it's rivals by being original.
In theory the setup shouldn't work, being a half ghost should be impossible even in the most mixed up cartoon world, but credit to Butch Hartman, he does it well.
Even when the most obvious character tropes are used to make up the cast, it's not immediately obvious when viewing the characters on screen.
For example, Sam is essentially Goth Lisa Simpson, but first impressions don't give that image so it makes you want to watch her more, the same can be said about other characters such as Jazz, Tucker and Danny himself.
The action can vary between good and predictable but never becomes boring as the diverse cast of villains can often save a bad episode.
Overall Danny Phantom is a good series bordering on great, it has a well written cast of characters, along side good music and an easy to digest plot. I only wish I viewed it when I did.