One thing I've noticed since I became a member here, is that the very first thing people ask is what's your favorite series or what's the first anime show you saw. Just about no one ever asks what your favorite manga is or which one you read first.
I find this rather interesting since there's a lot of stories out there that don't get made into a full animation. So obviously the only way you can access these stories is by reading the manga.
When a series is animated, there can often be a huge difference between the two. Like DNAngel and Yu-Gi-Oh. Both of them have quite a bit of material that didn't make it into the actual anime based on that series.
Anyway, one of the first manga's I ever read was Yu-Gi-Oh. How about you? If you haven't had a chance yet, head on over to OtakuBoards and take the time to check out the thread on this topic. It's always interesting to see which manga's people read first.