Welcome to the Anime Walk of Fame, a series of retrospectives on the many characters of the anime world. You'll see all your favorites along with a few that deserve more than their reputations give.

So sit back relax and enjoy the show.

The Embodiment of Cancer Ruri Hoshino

Other known Cancer
Violet Evergarden - Violet Evergarden
Nami - One Piece
Subaru Oozora - VTuber
Shouyou Hinata - Haikyuu
Izuku Midoriya - My Hero Academia
Sailor Moon - Sailor Moon
Himeno Awayuki - Pretear
Akko Kagari - Little Witch Academia
Akatsuki - Log Horizon
Kaoru Kamiya - Rurouni Kenshin
Houki Shinonono - Infinite Stratos
Touka Kirishima - Tokyo Ghoul
Aoi Sakuraba - Ai Yori Aoshi
Hiiragi Twins - Lucky Star
Canada - Hetalia Axis Powers
Popura Taneshima - Working!!
Hideri Kanzaki - Blend S
Lucia Nanami - Mermaid Melody Pichi Pichi Pitch
Yuri Tanima - Wedding Peach
Shunsui Kyoraku - Bleach

Cancers can effortlessly pick up the energies in a room and are highly sensitive to their environments, as well as extremely self-protective, while cold at first they will eventually open up.
Ruri spends a good portion of the anime as being the straight woman of the crew, she prefers to avoid madness and would rather just quietly get on with her job but as she develops she opens up more and eventually becomes the captain to a new team.
Ruri's journey from Science Officer to Captain is definitely the path of a Cancer.

Nice Design Doesn't Equal Success For Itsuki

Quite often a nicely designed character comes along who is instantly remembered for better or for worse, ask the entire extended Pokemon cast. But for Itsuki that's not the case.

The Aestivalis pilot of Martian Successor Nadesico Itsuki Kazama was doomed from the start, in her only appearance she takes lead character Akito's place after he walks out on the crew for the umpteenth time; Itsuki is pretty, dependable and has a design that fits in nicely with the series but when she goes into battle she is killed instantly when her enemy teleports, crushing her as a result as her body couldn't stand the extreme forces involved in teleporting.
The definition of cannon fodder, but remarkably while researching her character, she does have her own figure, so she did stand out but when competing against a large cast of desirable women on the Nadesico crew, there's just no room for the straight A woman soldier.

End